Recent advancements in artificial intelligence have led to the development of a groundbreaking tool called FaceAge, which uses facial analysis to predict cancer survival outcomes. This innovative approach, detailed in a study published in The Lancet Digital Health, offers new hope for personalised cancer treatment by assessing biological age through simple photographs.
Key Takeaways
FaceAge predicts biological age and survival outcomes for cancer patients using facial recognition technology.
Cancer patients often appear approximately five years older than their chronological age, correlating with poorer survival rates.
The tool has been validated on nearly 59,000 photos from healthy individuals and tested on about 6,200 cancer patients.
Patients with a FaceAge younger than their chronological age show better survival rates post-cancer therapy.
The Development of FaceAge
Researchers at Mass General Brigham created FaceAge to address the challenges faced by oncologists in assessing a patient's ability to withstand aggressive treatments. Traditional methods often rely on subjective assessments, which can lead to misjudgements based on a patient's appearance.
Dr. Ray Mak, a thoracic radiation oncologist and co-senior author of the study, expressed the need for a more objective tool. He noted that many patients who appear frail may actually be biologically younger than their chronological age, leading to potentially life-saving treatment being withheld.
How FaceAge Works
FaceAge employs deep learning algorithms trained on a vast database of facial images. The researchers analysed:
56,000+ photos of presumed healthy individuals
6,200+ photos of cancer patients taken at the start of their treatment
The analysis revealed that cancer patients typically have a higher FaceAge than non-cancer patients, with older FaceAge predictions linked to worse survival outcomes. For instance, patients whose FaceAge indicated they were over 85 had significantly lower survival probabilities compared to those appearing younger.
Clinical Implications
The implications of FaceAge are profound. By providing a quantitative measure of biological age, the tool can assist clinicians in making more informed treatment decisions. For example, it can help determine whether a patient is fit for aggressive therapies or if they require additional support, such as physical therapy, before treatment.
Hugo Aerts, another co-senior author, highlighted the potential of FaceAge to revolutionise clinical decision-making. He stated that a simple selfie could yield critical insights into a patient's health status, ultimately improving treatment outcomes.

Future Research and Considerations
While FaceAge shows promise, further research is necessary before it can be widely adopted in clinical settings. Key areas of focus include:
Testing the tool across diverse patient populations
Evaluating its effectiveness in different stages of cancer
Addressing potential biases related to ethnicity, gender, and cosmetic alterations
The research team is also exploring whether FaceAge can be used to predict other health conditions and overall lifespan, potentially expanding its application beyond oncology.
Conclusion
The introduction of FaceAge marks a significant step forward in the integration of AI into healthcare. As researchers continue to refine this technology, it holds the potential to enhance personalised medicine, offering hope to cancer patients and improving their chances of survival through more tailored treatment approaches.